PATHVIZON X50 - CLIA&DLCM - Products - Zhuhai Livzon Diagnostics Inc.

PATHVIZON X50

Overview

PATHVIZON X50 is a floor-standing dual-mode immunoassay analyzer designed for comprehensive autoimmune diagnostics. Integrating CLIA (Chemiluminescence Immunoassay) and DLCM (Digital Liquid Chip Method) in one system, it supports both routine chemiluminescence testing and high-throughput multiplex autoantibody detection.
In CLIA mode, the system uses an indirect chemiluminescence method based on AMPPD and alkaline phosphatase, supporting sandwich, competitive, and indirect immunoassay formats for qualitative or quantitative detection of target analytes in human serum or plasma samples. In DLCM mode, the analyzer applies a magnetic barcode immuno-fluorescence principle: multiple antigen- or antibody-coated magnetic barcode liquid chips are contained in a single reaction, allowing different autoantibody targets to be identified and measured simultaneously through fluorescence imaging and barcode recognition. This enables efficient multiplex testing with fast turnaround and flexible laboratory workflow.
With its dual-mode design, random-access workflow, scalable modular connectivity, and compatibility with autoimmune assay panels, PATHVIZON X50 provides laboratories with an integrated solution for high-efficiency, high-performance autoantibody testing.

Key Features

• High-Throughput Dual-Mode Testing

Supports both CLIA and DLCM, delivering up to 300-400 tests/hour in CLIA mode and up to 2000 tests/hour in DLCM mode for maximum laboratory efficiency.

• Fast and Reliable Results

Provides rapid turnaround with a first report time of 21 (CLIA)/37 (DLCM) minutes, one stop complete solution for auto-antibody detection.

• Scalable Modular Connectivity

Modular connection of up to 4 units, and build the World's 1st Autoimmune Dx Streamline -seamless integration with PATHVIZON F7 or TLA-ready laboratory setup.

Test Menu

	Panel	Test Item
CLIA (Autoimmune Diagnostics)	CTD	dsDNA, Nucleosome, Histone, CENP-B, Sm, P0, SS-A/Ro52kD, SS-A/Ro60kD, SS-B/La, PCNA, AMA M2, Scl-70, U1-snRNP, Jo-1, PM-Scl, Mi-2, Ku, Clq
	RA	CCP, MCV, *RA33
	APS	β2GP1 (IgG, IgM, IgA, Screen), Cardiolipin (IgG, IgM, IgA, Screen), β2GP1-D1-IgG, aPS/PT (IgG, IgM)
	Vasculitis	MPO, PR3, GBM
	Myositis	MDA5
	Diabetes	GAD, IA2, ICA, IAA, *Zn8
CLIA (Specialized Assay Menu)	Tuberculosis	TB-IGRA
	Alzheimer's Disease	pTau-181, Aβ 1-40, Aβ1-42, pTau-217, GFAP, *Nfl
	Metabolism	T1DM: Anti-GAD, Anti-IA2, Anti-ICA, Anti-IAA; *Vit-D
	Respiratory & Lung Diseases	M. Pneumonia IgM/IgG, C. Pneumonia IgM/IgG, *KL-6
	Liver Diseases	AFP, AFP-L3, PIVKA/DCP, HBCrAg, GPC-3, ELF
	Cytokines	IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70, IL-17A, IFN-α, IFN-γ, TNFα, IL-2R, IL-18
DLCM	ANA, Antinuclear Antibody	dsDNA, Nucleosome, Histone, CENP-B, Sm, P0, SS-A/Ro52kD, SS-A/Ro60kD, SS-B/La, PCNA, AMA M2, Scl-70, U1-snRNP, Jo-1, PM-Scl, Mi-2, Ku
	RA, Rheumatoid arthritis	CCP, MCV, *RA33
	ANCA, Vasculitis	MPO, PR3, GBM
	ALD, Autoimmune Liver Disease	AMA M2, sp100, gp210, LKM-1, LC-1, SLA/LP, SS-A/Ro52kD
	MYO, Myositis	TIF1γ, MDA5, NXP2, SAE1, PM-Scl100, PM-Scl75, Jo-1, SRP, PL-7, PL-12, EJ, OJ, SS-A/Ro52kD, HMGCR, *Ku

*ongoing

Specifications

Specification	Details
Testing Speed (CLIA)	Single module: 400 tests/hr; Cascaded: Up to 1600 tests/hr
Testing Speed (DLCM)	Single module: 100 tests/hr; Cascaded: Up to 400 tests/hr
Sample Capacity	600 samples (dual-layer, 30 sample racks per layer)
Reagent Capacity	36 CLIA positions, 18 multi-plex positions
Reagent Refrigeration	Set at 5°C (deviation within ±3°C)
Incubation Temp	Set at 37°C (deviation within ±0.5°C)
Reaction Cup Capacity	3000 cups per analysis host module
Dimensions (L x W x H)	1880 mm x 1140 mm x 1280 mm
Weight	Host Module: 450 kg; Sample Management Module: 120 kg

Ordering Information

Cat. No.	Product Name	Spec.	Certificate
C2011	PATHVIZON X50	1 set	NMPA